Start Your Own Franchise Business in Missouri

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Cleaning Franchises

Jani-King

Jani-King provides global commercial cleaning services with franchise opportunities for unit, regional, and international ownership.

Min. Investment

$16,250

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Cleaning Franchises

Spaulding Decon

Spaulding Decon provides biohazard, restoration, and specialty cleaning services with diversified revenue streams and strong franchisee support.

Min. Investment

$175,000

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Pet Care & Food

The Dog Wizard

The Dog Wizard provides comprehensive dog training services with a mobile-based model, low overhead, and strong franchisee support.

Min. Investment

$85,400

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Pet Care & Food

Pet Butler

Pet Butler provides pet waste removal and optional pet care services with a mobile-first, home-based franchise model and recurring revenue.

Min. Investment

$79,065

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Pet Care & Food

Dogtopia

Dogtopia provides dog daycare, boarding, and wellness services with membership-based recurring revenue and strong franchisee support.

Min. Investment

$608,000

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Sign and Print

Minuteman Press

Minuteman Press provides printing and marketing services with a low-investment, home-based model, backed by strong support and recurring revenue.

Min. Investment

$81,000

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Cleaning Franchises

OpenWorks

OpenWorks provides commercial cleaning and facilities services with a scalable, home-based model and guaranteed customers from Day One.

Min. Investment

$15,000

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Care & Elderly Services

Home Instead

Home Instead provides relationship-based senior care services with advanced technology and a global support network, ideal for dedicated franchise operators.

Min. Investment

$98,000

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Fitness & Gym Franchises

Orangetheory Fitness

Orangetheory Fitness combines HIIT workouts with heart-rate monitoring in a scalable boutique format, backed by Purpose Brands’ global operations and support.

Min. Investment

$822,000

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Beauty & Health

Great Clips

Great Clips offers affordable walk-in haircuts with efficient salon operations, backed by a proven, recession-resistant business model.

Min. Investment

$136,900

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Explore top franchises in Missouri across a range of industries

The state of Missouri has a sizable population of 6.1 million people, making for an attractive and solid consumer base. And with 2.4 million households with a median household income of $71,520, it’s definitely a great location to consider if you’re looking for franchise opportunities in Missouri. There are a staggering number of small businesses, adding up to around 520,000, meaning that the business environment is friendly and supportive for new and aspiring entrepreneurs looking to make it in the state.


Some of the main reasons to consider Missouri the home state of your franchise business are:

  • Missouri’s economy ranks 22nd in size among US states.
  • The state’s real gross domestic product (GDP) growth rate in the first quarter of 2023 was 2.6% per year or a monetary value of $393.3 billion. It accounts for 1.5% of the US’s total economy.
  • The low unemployment rate of 3.1% is lower than the national average.
  • Missouri’s largest industry by GDP is manufacturing (such as food and beverages, chemicals, and electronics) although other strong and prominent industries include agriculture. Additionally, the service sector, including government, financial services, and health services, plays a vital role in the state’s economy, with tourism also showing promising growth.
  • The Missouri 2030 initiative has been launched as a strategic plan to prepare the workforce, foster a competitive business climate, and unite the business community.

Some of the state’s largest cities include Kansas City, St. Louis, Springfield, Columbia, and Independence with the state capital being Jefferson City.

When it comes to St. Louis, the city offers a robust corporate environment for business services franchises. In particular, the city is well-suited to consulting firms, IT services, and other B2B services. In addition, St. Louis has a vibrant retail scene. In fact, total retail expenditure in 2023 was valued at $2.98 billion. This is a strong signal to prospective franchisees looking at retail franchises that include restaurants, grocery stores, or entertainment venues. Other areas worth considering in St. Louis include home services, furnishing, and real estate.

Meanwhile, Kansas City is seeing a rise in work-from-home opportunities, presenting a fertile ground for home-based or delivery-based entrepreneurs and businesses.

Missouri’s business landscape:

  • Thriving healthcare: The healthcare and social assistance sector remains a major employer, offering potential for businesses operating in related fields.
  • Manufacturing resurgence: While traditionally strong, manufacturing experienced a dip in recent years but is now showing signs of revival, presenting opportunities for related businesses.
  • Tech sector development: While not as prominent as in some other states, Missouri’s tech industry is witnessing growth, offering opportunities in areas like cybersecurity and data analytics.

Challenges and key considerations:

  • Workforce development: Attracting and retaining skilled workers, particularly in tech and other specialized fields, remains a challenge for Missouri businesses.
  • Rural vs. urban divide: Economic opportunities and growth are concentrated more in urban areas, leaving some rural communities lagging behind. Bridging this gap could unlock further potential.
  • Infrastructure needs: Investments in infrastructure are crucial for maintaining Missouri’s competitiveness, particularly in transportation and broadband access.

Missouri is home to a diverse range of franchise opportunities, making it a great place for entrepreneurs to invest. The state offers many industries to choose from, including:

Overall, the landscape and environment for Missouri franchises is healthy and robust, offering aspiring entrepreneurs amazing franchise business opportunities. And just a few of the reasons why you should consider franchises in Missouri when ready to start a business are that franchising comes with a proven and tested business model that offers you a solid foundation for your new venture.

The fact that the business model has been refined and tested over the years indicates a stronger likelihood of success for you. This, coupled with an established industry reputation through a recognized brand name, ensures customers are drawn to your business and that finding and retaining them becomes easier.

Other great reasons to consider the franchises for sale in Missouri that we present to you on our franchise portal include that franchising in the state is accompanied by intensive yet helpful and insightful training, which sets you up for success. This is bolstered by continued and ongoing support from both the franchisor and the wider franchisee network community, meaning you’ll never feel like you’re in business alone.

And to add the cherry on top of the cake, there are affordable franchises, which means that you can choose a low-cost franchise to suit your budget and to ensure your road to business ownership remains unhindered yet affordable.So, when you’re looking for available franchises for sale in Missouri, get in touch with our team at Franchise Fame. We have extensive industry experience and can help guide you through the process seamlessly.

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